Refutation of Minot’s theory 353
The second division of the nuclear spindle 355 involves a reduction of the ancestral germ-plasms
The theoretical necessity for such reduction 356
Phyletic origin of the germ-plasms in existing 357 species
The necessary reduction takes place by a special 358 form of nuclear division
The division which causes this reduction has 360 probably been already observed
Van Beneden’s and Carnoy’s observations 360
Two different physiological effects of 364 karyokinesis
Significance of direct nuclear division 365
Arguments in support of the view that the division 367 of the egg-nucleus which causes reduction must occur at the end of ovogenetic development
Such nuclear division is to be found in the 368 formation of the second polar body
History of the origin of this view 368
