Gene

A gene is a stretch of DNA that carries the instructions for a product, usually a protein or a functional RNA. Wilhelm Johannsen introduced the word in 1909 for a unit of heredity whose physical nature was then unknown; the molecular definition arrived decades later. The word is still used in two ways that do not fully line up: the classical gene, inferred from patterns of inheritance, and the molecular gene, a sequence with a start and an end, and the mismatch between them is an active dispute.

Why it matters

It is the single most reused word in biology, and knowing that it names two different things prevents most of the confusion beginners have with genetics papers.

Also written: genes, genic

Where it comes up

Read about Gene on Wikipedia

Sources

  1. Gene Wikipedia
  2. The Gene Stanford Encyclopedia of PhilosophySets out the classical and molecular gene concepts and why they do not reduce to each other.
  3. Gene NHGRI Talking Glossary of Genetic Terms

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Gene: definition and where it comes up | amphi